Bayer Pharma AG - Sat May 19 16:57:33 CEST 2012

Ultrasound (US)

Cavernous hemangioma

Cavernous hemangioma is the most common benign tumor of the liver. It is reported with an incidence of 20% in the general population. It is also a frequent incidental finding in the investigation of other diseases and is mostly asymptomatic.

MRI appearance of a cavernous hemangioma without (pre-contrast) and with Primovist®

MRI represents the ideal diagnostic tool when characterizing hemangiomas. Hemangiomas have low signal intensity on T1-weighted images and high signal intensity on T2-weighted images. Hemangiomas have a well-defined lobular border (left-hand-side).

In the liver-specific phase, 20 min after Primovist® administration, hemangiomas are hypointense (dark areas) to the surrounding parenchyma and do not show an uptake of the agent (right-hand-side).

Cavernous hemangioma

Precontrast: T1-weighted: hypointense lesion vs. liver parenchyma
Precontrast: T1-weighted: hypointense lesion vs. liver parenchyma
After injection, T1-weighted, liver-specific phase: hypointense lesion
After injection, T1-weighted, liver-specific phase: hypointense lesion

Therapy

If there is concern regarding rupture, the lesions can be excised quite safely by an experienced liver surgeon familiar with hepatic malformations. More often than not, conservative medical observation is advised (imaging follow-up) in order to observe growth. Other treatment options are embolization and steroids.

Primovist

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Liver MRI with Primovist®

Typical T1-weighted MR liver image

High diagnostic accuracy due to liver-specific contrast media

Ultrasound

Ultrasound of the liver (HCC)

Ultrasound of the liver provides lower diagnostic ability

http://www.liver-imaging.com/scripts/pages/en/detecting_and_characterizing_liver_lesions/benign_lesions/cavernous_hemangioma/index.php
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